Asbestos is a mineral that occurs naturally in the form of bundles, lämmöksi. These fibers can be converted to that are resistant to heat, chemicals and electricity is not insulated is thin threads. The essence of asbestos is based on the Silicon compound with several options such as Amphibole, chrysotile ... etc.
Asbestos can be found on the construction of the cement, insulation, roofing, boilers, steam pipes, hot water pipes and a host of other products. in the 20th century was linked to respiratory problems, asbestos, asbestosis, which were in the series. in the 1950s was made later, asbestos and mesothelioma. Asbestos is now found as one of the most effective cancer in our environment. Yet, even today, asbestos is found in many products for everyday life (ex Fireproof clothing, caulk., switch plates, brake pads, etc..)
Who are at risk of developing mesothelioma?
The asbestos is particularly dangerous for persons who work regularly with it. When asbestos is disturbed, the fibres are released in the atmosphere and the people that the environment through inhalation. Construction work (for example, the renovation of old buildings constructed with asbestos cement), pipefitting and other such works can release asbestos fibres, which can then be sent through inhalation. Also, the secondary exposure is known. The dust of the clothing and hair of workers to asbestos fibres may be collected by their family members. It is known that exposure as low as possible, two months is sufficient to result in mesothelioma 30-40 years down the line.
Factors affecting the risk of mesothelioma
A number of factors determine whether asbestos exposure cause mesothelioma cancer in the future:
* Dose (how much asbestos is inhalation)
* Duration (the length of exposure to asbestos)
* Asbestos fibres (for mesothelioma, the fibres are considered to be more dangerous, because the longer they remain in the lungs, and the mesothelial layer move Amphibole) type.
* The unique risk factors such as smoking and preexisting lung conditions
How does asbestos cause mesothelioma cancer?
After inhalation of asbestos fibres cause cells to die, cause the lungs become scarred. Asbestos fibres are slow on the alveoli, and eventually the mesothelium.
For some time now, researchers have been unable to determine the exact pathway of asbestos fibres, which cause cancer. This is because asbestos is thought to be necrotic nature (that is, it kills cells). The dead cells to multiply and produce tumours. It is only recently that this is the paradox of 2010, was resolved. Asbestos fibres cause programmed cell necrosis, which is released from the molecule of high mobility group box 1 (HMGB-1) protein is known. The reaction of HMGB1 for the start of the Prostate, which lead to tumor growth, but the genes and factors of production.
The genetic damage, including those parts that regulate cell reproduction DNA in cells. Cells will begin to play the uncontrollably which form tumours. The growth factors in the result, therefore, be encouraged to expand their tumours of mesothelioma and lung cancer, cancer, depending on the site of injury.
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